Old Human Cells Rejuvenated – resveratrol in dark choco, berries and grapes

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Old Human Cells Rejuvenated in Breakthrough Discovery on Aging

Summary: Resveratrol analogues appears to switch splicing factors back on, causing cells to look younger, start rejuvenating and behaving like young cells within hours of exposure, a new study reports.Source: University of Exeter.

A team led by Professor Lorna Harries, Professor of Molecular Genetics at the University of Exeter, has discovered a new way to rejuvenate inactive senescent cells. Within hours of treatment the older cells started to divide, and had longer telomeres – the ‘caps’ on the chromosomes which shorten as we age.

The researchers applied compounds called resveratrol analogues, chemicals based on a substance naturally found in red wine, dark chocolate, red grapes and blueberries, to cells in culture.

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This discovery, funded by the Dunhill Medical Trust, builds on earlier findings from the Exeter group that showed that a class of genes called splicing factors are progressively switched…

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