According to researchers, the frequency of mastication has dramatically decreased along with changes in dietary habits. Masticatory stimulation has influence on the development of the central nervous system as well as the growth of maxillofacial tissue in children. Deterioration of masticatory function due to aging and the consequent reduction of brain function has become major problems. Although the relationship between mastication and brain function is potentially important, the mechanism underlying is not fully understood.

In order to prevent brain function disorders, including those relating to memory and learning, it is an urgent task to elucidate the linkage between masticatory function and brain function.

Researchers found that growth of the maxillofacial bone and muscle…