Altering The Immune System to Reverse Paralysis

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Summary: An experimental treatment can generate immune cells that migrate to the brain and prevent attacks against myelin, allowing mice the ability to regain walking skills.

Source: American Chemical Society.

In the ultimate betrayal, one’s own immune system can turn against the protective sheath that envelops neurons in the brain, leaving the body paralyzed. Researchers have developed an experimental treatment that tames the wayward immune system in rodents, returning the power of movement to paralyzed mice. The approach may someday combat autoimmune diseases, such as multiple sclerosis and type 1 diabetes, in humans.

The researchers will present their work today at the 253rd National Meeting & Exposition of the American Chemical Society (ACS). ACS, the world’s largest scientific society, is holding the meeting here through Thursday. It features more than 14,000 presentations on a wide range of science topics.

“The problem with current immunotherapies is that they aren’t specific,” says…

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